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Zhonghua Wai Ke Za Zhi · Nov 1991
Randomized Controlled Trial Comparative Study Clinical Trial[Hemodynamic effects of etomidate in cardiac surgery during induction of anesthesia].
- D J Sun.
- Renji Hospital, Shanghai Second Medical University.
- Zhonghua Wai Ke Za Zhi. 1991 Nov 1; 29 (11): 682-4, 718.
AbstractFor comparison of the induction effects of domestic etomidate on hemodynamics with gamma-OH, each group of thirty patients undergoing either repair of ASD or MVR was randomly selected. Certain hemodynamic parameters involving CI, SI, IC, MAP, HR and SVR (cardiac index, stroke volume index, index of contractility, mean artery pressure, heart rate and systemic vascular resistance) were followed throughout the course of induction. The results showed that HR decreased in gamma-OH 2 minutes after intravenous injection (P less than 0.05) but not in etomidate. MAP and SVR decreased 5 minutes after the administration of drugs (P less than 0.05), while the others showed no significant changes. We conclude that etomidate is superior to gamma-OH in patients for cardiac operations during induction.
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