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- Ryan J Barrett, Lee Sandquist, Boyd F Richards, and Teck M Soo.
- Providence Hospital and Medical Centers, Department of Neurological Surgery, Southfield, MI, USA.
- Turk Neurosurg. 2014 Jan 1; 24 (4): 613-7.
AimTo evaluate the feasibility of this novel surgical approach for treatment of cervical discitis and vertebral osteomyelitis.Material And MethodsThis is a report of two patients who underwent anterior cervical decompression for discitis and vertebral osteomyelitis (DVO) with cervical spine reconstruction with polymethylmethacrylate impregnated with antibiotics (AI-PMMA).ResultsBoth patients had successful procedures that were followed by 6 weeks of intravenous antibiotics. Stabilization and eradication of infection was achieved with clinical and radiographic stabilization seen in both. Follow-up is greater than 18 months and both patients remain off antibiotics.ConclusionThe described technique using AI-PMMA offers immediate structural stability and local delivery of high concentration of antibiotics. Use in two patients has demonstrated a cost effective, long-term biomechanically stable construct and infection control.
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