• J. Am. Vet. Med. Assoc. · Dec 1980

    Case Reports

    Warfarin anticoagulation in the horse.

    • E A Scott, T D Byars, and A M Lamar.
    • J. Am. Vet. Med. Assoc. 1980 Dec 1; 177 (11): 1146-51.

    AbstractThe hematologic and clinical effects of anticoagulation with warfarin were documented in 4 horses. All of the animals had thrombophlebitis (external jugular vein). Measures of coagulation were monitored, with a prothrombin time of 1.5 to 2.5 x base-line value being used as the effective range of anticoagulation. Recanalization was achieved in 2 of 4 cases. Hemorrhage, both subcutaneous and through a surgical incision, was a complication. Vitamin K1, an antidote to warfarin toxicosis, was administered intravenously to reverse anticoagulation and to control hemorrhage.

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