• J Subst Abuse Treat · Jan 2015

    Denial of urinalysis-confirmed opioid use in prescription opioid dependence.

    • E Yvette Hilario, Margaret L Griffin, R Kathryn McHugh, Katherine A McDermott, Hilary S Connery, Garrett M Fitzmaurice, and Roger D Weiss.
    • Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, MA 02478, USA.
    • J Subst Abuse Treat. 2015 Jan 1; 48 (1): 85-90.

    AbstractAlthough research has generally supported the validity of substance use self-reports, some patients deny urine-verified substance use. We examined the prevalence and patterns of denying urinalysis-confirmed opioid use in a sample of prescription opioid dependent patients. We also identified characteristics associated with denial in this population of increasing public health concern. Opioid use self-reports were compared with weekly urinalysis results in a 12-week multi-site treatment study for prescription opioid dependence. Among those who used opioids during the trial (n=246/360), 44.3% (n=109) denied urinalysis-confirmed opioid use, although usually only once (78%). Overall, 22.9% of opioid-positive urine tests (149/650) were denied on self-report. Multivariable analysis found that initially using opioids to relieve pain was associated with denying opioid use. These findings support the use of both self-reports and urine testing in treating prescription opioid dependence.Copyright © 2014 Elsevier Inc. All rights reserved.

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