• Paediatric anaesthesia · Jan 1999

    Case Reports

    Extrapyramidal side-effects from droperidol mixed with morphine for patient-controlled analgesia in two children.

    • W Habre, D Wilson, and C M Johnson.
    • Princess Margaret Hospital for Children, Perth, Western Australia.
    • Paediatr Anaesth. 1999 Jan 1; 9 (4): 362-4.

    AbstractWe report two cases of extrapyramidal reactions occurring in children following the use of droperidol in combination with morphine for patient-controlled analgesia (PCA). Symptoms appeared 38 and 27 h, respectively, after commencement and after a total dose of 0.14 mg.kg-1 and 0.17 mg.kg-1, respectively. Although effective and safe in adult patients, we recommend caution with the use of droperidol-morphine mixtures for PCA in paediatric patients.

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