• Anaesthesia · Jun 1994

    Case Reports

    Response to suxamethonium during propofol-fentanyl-N2O/O2 anaesthesia in a patient with active myasthenia gravis receiving long-term anticholinesterase therapy.

    • L E Vanlinthout, E N Robertson, and L H Booij.
    • Institute for Anaesthesiology, University Hospital of Nijmegen, The Netherlands.
    • Anaesthesia. 1994 Jun 1; 49 (6): 509-11.

    AbstractWe describe the effect of repeated suxamethonium doses during propofol-fentanyl-N2O/O2 anaesthesia in a 29-year-old woman with active myasthenia gravis receiving chronic pyridostigmine therapy. Despite adequate pre-operative pseudocholinesterase activity, suxamethonium resistance occurred. Neither bradycardia nor residual neuromuscular block were seen after repeated doses of suxamethonium.

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