• B Gómez, S Capapé, F J Benito, J Landa, Y Fernández, C Luaces, O Serrano, M C Freijó, M E May, V Aldecoa, and miembros del Grupo de Trabajo de Analgesia y Sedación de la SEUP.
• Servicio de Urgencias de Pediatría, Hospital de Cruces, Barakaldo, Bizkaia, España. borja.gomezcortes@osakidetza.net
• An Pediatr (Barc). 2011 Aug 1; 75 (2): 96-102.

ObjectivesPrimary Objectivesto assess the safety and the effectiveness (analysing the behaviour of the patient) with the use of nitrous oxide during the performance of painful procedures in the Paediatric Emergency Departments (PED); secondary objectives: to evaluate the manageability of the method and its acceptance by both the medical team and the patient.Patients And MethodsPost-marketing observational, prospective, multicentre, non-randomised and open (November 2007-December 2008) study, which involved seven national PED. We included patients between 2 and 18 years-old on whom a painful procedure was performed in the PED and nitrous oxide was used.ResultsA total 213 patients were included (27,2% < 5 years). Patient behaviour was considered «good/very good» in 79,7%, with no statistically significant difference in relation to the procedure performed. Patient behaviour was more often classified as «bad/accept with difficulty» among those < 5 years (33.3% vs 15.1%, P=.006). Adverse events occurred in 17 cases (7.9%), with no significant difference in the rate in relation to the age, fasting or not or in association with other drugs; the most frequent were dizziness and/or headache (10), followed by vomiting (3). The administration was considered easy by the medical team in the 96.6% of the cases. Parents would accept the use of nitrous oxide in their child in a similar situation in 92.7% of the cases.ConclusionsAdministration of nitrous oxide achieves proper sedation and analgesia during painful procedures, especially in children older than 5 years. Adverse events reported were few, mild and expected. Most parents would accept its use again in a similar situation.Copyright © 2009 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.

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