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J Bone Joint Surg Br · Jul 1996
Comparative StudyInfluence of materials for fixation implants on local infection. An experimental study of steel versus titanium DCP in rabbits.
- S Arens, U Schlegel, G Printzen, W J Ziegler, S M Perren, and M Hansis.
- AO/ASIF Research Institute, Davos, Switzerland.
- J Bone Joint Surg Br. 1996 Jul 1; 78 (4): 647-51.
AbstractResistance to infection may be influenced by foreign bodies such as devices for fracture fixation. It is known that stainless steel and commercially-pure titanium have different biocompatibilities. We have investigated susceptibility to infection after a local bacterial challenge using standard 2.0 dynamic compression plates of either stainless steel or titanium in rabbit tibiae. After the wounds had been closed, various concentrations of a strain of Staphylococcus aureus were inoculated percutaneously. Under otherwise identical experimental conditions the rate of infection for steel plates (75%) was significantly higher than that for titanium plates (35%) (p < 0.05).
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