• Rheumatol. Int. · Jun 2008

    Case Reports

    Acute dermatomyositis associated with generalized subcutaneous edema.

    • Ki-Hong Lee, Sung-Ryoun Lim, Yeon-Joo Kim, Kyung-Ju Lee, Dae-Seong Myung, Hae-Chang Jeong, Woong Yoon, Shin-Seok Lee, and Yong-Wook Park.
    • Department of Rheumatology, Chonnam National University Medical School and Hospital, Dong-Ku, Gwangju, Republic of Korea.
    • Rheumatol. Int. 2008 Jun 1; 28 (8): 797-800.

    AbstractGeneralized subcutaneous edema is an uncommon manifestation of inflammatory myopathy. We report a 48-year-old female patient who presented with severe generalized edema, an erythematous skin rash, dysphagia and proximal muscle weakness. She was diagnosed with dermatomyositis from the clinical signs, increased muscle enzymes, electromyographic findings and a muscle biopsy. Magnetic resonance imaging revealed increased signal intensity in the muscular and subcutaneous layers. The conditions causing generalized edema were excluded. It was concluded that the generalized edema was secondary to dermatomyositis. Aggressive treatments with high-dose glucocorticoids and immunosuppressive agents were used to control the severe subcutaneous edema.

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