• Anesthesiology · Mar 2005

    Review

    Pharmacogenetics of anesthetic and analgesic agents.

    • Stephen N Palmer, N Martin Giesecke, Simon C Body, Stanton K Shernan, Amanda A Fox, and Charles D Collard.
    • Department of Cardiovascular Anesthesia, Texas Heart Institute, St. Luke's Episcopal Hospital, Houston 77030, USA.
    • Anesthesiology. 2005 Mar 1; 102 (3): 663-71.

    AbstractPredicting a patient's response to a particular drug has long been a goal of clinicians. Rapid advances in molecular biology have enabled researchers to identify associations between an individual's genetic profile and drug response. Pharmacogenetics is the study of the molecular mechanisms that underlie individual differences in drug metabolism, efficacy, and side effects. The pharmacogenetics of commonly used anesthetic and analgesic agents are reviewed.

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