• Gynecol. Obstet. Invest. · Jan 1989

    Comparative Study

    Mode of delivery and lymphocyte beta 2-adrenoceptor density in parturients and newborns.

    • M Santala.
    • Department of Obstetrics and Gynaecology, Kuopio University Central Hospital, Finland.
    • Gynecol. Obstet. Invest. 1989 Jan 1; 28 (4): 174-7.

    AbstractTwenty-six women with uncomplicated pregnancy at term were selected for the study. Nine had spontaneous vaginal delivery without medication, 8 elective caesarean section under epidural and 9 under general anaesthesia. The results clearly demonstrate that newborns have lower lymphocyte beta 2-adrenoceptor density than their mothers. In vaginally delivered newborns the lymphocyte beta 2-adrenoceptor density was 38%, in the caesarean section group with general anaesthesia 27%, and with epidural anaesthesia 22% lower than in the corresponding mother group. Vaginally delivered newborns have lower lymphocyte beta 2-adrenoceptor density than those delivered by caesarean section. A plausible explanation is the down-regulation of the beta 2-adrenoceptors during labour and delivery.

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