• Diagn Pathol · Jan 2012

    Case Reports

    Pathological femoral fractures due to osteomalacia associated with adefovir dipivoxil treatment for hepatitis B: a case report.

    • Motoyuki Tanaka, Takao Setoguchi, Yasuhiro Ishidou, Yoshiya Arishima, Masataka Hirotsu, Yoshinobu Saitoh, Shunsuke Nakamura, Hironori Kakoi, Satoshi Nagano, Masahiro Yokouchi, Junichi Kamizono, and Setsuro Komiya.
    • Department of Orthopaedic Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
    • Diagn Pathol. 2012 Jan 1; 7: 108.

    UnlabelledWe present a case of a 62-year-old man who underwent total hip arthroplasty for treatment of pathologic femoral neck fracture associated with adefovir dipivoxil-induced osteomalacia. He had a 13-month history of bone pain involving his shoulders, hips, and knee. He received adefovir dipivoxil for treatment of lamivudine-resistant hepatitis B virus infection for 5 years before the occurrence of femoral neck fracture. Orthopedic surgeons should be aware of osteomalacia and pathological hip fracture caused by drug-induced renal dysfunction, which results in Fanconi's syndrome.Virtual SlidesThe virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/1600344696739249.

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