• Acad Emerg Med · Mar 2005

    Emergency physician recognition of adverse drug-related events in elder patients presenting to an emergency department.

    • Corinne Michèle Hohl, Caroline Robitaille, Vicky Lord, Jerrald Dankoff, Antoinette Colacone, Luc Pham, Anick Bérard, Jocelyne Pépin, and Marc Afilalo.
    • Emergency Department, Vancouver General Hospital, 885 West 12th Avenue, Vancouver, British Columbia, Canada. corinnehohl@yahoo.ca
    • Acad Emerg Med. 2005 Mar 1; 12 (3): 197-205.

    ObjectivesThe authors examined the ability of emergency physicians (EPs) to recognize adverse drug-related events (ADREs) in elder patients presenting to the emergency department (ED).MethodsThis was a prospective observational study of patients at least 65 years of age who presented to the ED. ADREs were identified using a validated, standardized scoring system. EP recognition of ADREs was assessed through physician interview and subsequent chart review.ResultsA total of 161 patients were enrolled in the study. Thirty-seven ADREs were identified, which occurred in 26 patients (16.2%; 95% confidence interval [CI] = 10.5% to 22.0%). The treating EPs recognized 51.2% (95% CI = 35.2% to 67.4%) of all ADREs. There was better recognition of those ADREs related to the patient's chief complaint (91%; 95% CI = 74.1% to 100%) as compared with recognition of ADREs that were not associated with the chief complaint (32.1%; 95% CI = 14.8% to 49%). EPs recognized six of seven severe ADREs (85.7%), 13 of 23 moderate ADREs (56.5%; 95% CI = 36.8% to 77%), and none of the mild ADREs. Recognition of ADREs varied with medication class.ConclusionsEP performance was superior at identifying severe ADREs relating to the patients' chief complaints. However, EP performance was suboptimal with respect to identifying ADREs of lower severity, having missed a significant number of ADREs of moderate severity as well as ones unrelated to the patients' chief complaints. ADRE detection methods need to be developed for the ED to aid EPs in detecting those ADREs that are most likely to be missed.

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