• Gena C Dunivan, Brent A Parnell, AnnaMarie Connolly, Mary L Jannelli, Bethany Jablonski Horton, and Elizabeth J Geller.
• Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, 3032 Old Clinic Building, Campus Box 7570, Chapel Hill, NC 27599-7570, USA.
• Int Urogynecol J. 2011 Apr 1; 22 (4): 433-8.

Introduction And HypothesisThe aim of this study was to investigate the impact of retropubic injection of 0.125% bupivacaine during midurethral sling placement on postoperative pain.MethodsA randomized, double-blind trial of 42 women undergoing midurethral sling for stress incontinence was conducted. The intervention group received an injection of 0.125% bupivacaine in the retropubic space prior to midurethral sling placement, while the control group received no injection. Pain scores were recorded via a 10-cm visual analog scale at 2, 6, and 24 h postoperatively.ResultsPain scores were lower in the bupivacaine group compared to the control group at 2 h (1.9 versus 2.6, p = 0.05). Mean pain scores were similar at all other time points (all p > 0.45). Participants in both groups used similar amounts of pain medication in the hospital, except that patients in the bupivacaine group used more PO non-steroidal anti-inflammatory drugs (p = 0.047).ConclusionsRetropubic injection of 0.125% bupivacaine at the time of midurethral sling placement decreases short-term postoperative pain.

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