• Arkhiv patologii · Nov 2003

    Clinical Trial

    [Morphological diagnosis of the inhalation trauma and criteria of efficacy of the endobronchial laser therapy based on the biopsy material].

    • I E Galankina, I V Dement'eva, T P Pinchuk, and G A Maĭorov.
    • N. V. Sklifosovsky Research Institute of Emergency Care, 129010, Moscow.
    • Arkh. Patol. 2003 Nov 1; 65 (6): 8-13.

    AbstractThe results of 424 biopsies obtained at fibrobronchoscopy (FBS) from 45 patients with inhalation trauma (IT) are presented. The standard and endoscopic laser treatment (ELT) have been used (24 and 21 patients, respectively). It is demonstrated that precise visual assessment of IT severity is possible under dynamic endoscopic observation only. Healing of mucous defects of the tracheo-bronchial tree was shorter in the ELT group. Morphologically, early and continuous ELT was not associated with signs of severe purulent inflammation and, therefore, produced no early additional, damage to the wall. This may explain accelerated formation of the granulation tissue at the ulcer bottom and epithelization at the margin areas.

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