• Anesthesia and analgesia · Mar 1993

    Randomized Controlled Trial Comparative Study Clinical Trial

    Induction of anesthesia with sevoflurane, nitrous oxide, and oxygen: a comparison of spontaneous ventilation and vital capacity rapid inhalation induction (VCRII) techniques.

    • M Yurino and H Kimura.
    • Department of Anesthesia, Asahikawa Medical College, Hokkaido, Japan.
    • Anesth. Analg. 1993 Mar 1; 76 (3): 598-601.

    AbstractIn this study, the vital capacity rapid inhalation induction of anesthesia (VCRII) technique and the conventional spontaneous inhalation induction technique, each using 4.5% sevoflurane in nitrous oxide and oxygen, were compared. The VSRII group (n = 32) and conventional group (n = 32) were each tested on unpremedicated volunteers. VCRII required only half the time of conventional inhalation induction (54 s and 108 s, respectively), and was not associated with cardiovascular instability. Each of the two techniques was found acceptable by most of the volunteers studied (more than 80%). However, sevoflurane is best used with the VCRII technique because VCRII resulted in fewer excitement movements that could lead to severe complications and pronounced excitement.

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