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- Jafar Abunasser and Robert Brown.
- Department of Internal Medicine, Saint Vincent's Medical Center, Bridgeport, USA.
- Conn Med. 2010 Jan 1; 74 (1): 23-6.
ObjectiveTo assess the risks associated with removal of more than 1 liter of pleural fluid in one settingwithout intrapleural pressure monitoring.DesignSingle-center retrospective chart review.SettingMedium-sized community-based teaching hospital in Bridgeport, Connecticut.MethodsWe reviewed thoracenteses performed between February 2004 and March 2006, and documentedtherates of hypotension, pneumothorax, bleeding, andre-expansion pulmonaryedema.ResultsA total of 300 thoracenteses performed on 237 patients were analyzed, of which 137 were large volume (>1 liter) and 163 were small volume (<1 liter). There was no statistically significant increase in risk of pneumothorax, hypotension, or bleeding with large-volume thoracentesis. One case of radiographically-identified re-expansion pulmonary edema occurred when 2600 mL of fluid were removed.ConclusionLarge-volume thoracentesis is a safe procedure that is comparable in risk to small volume thoracentesis.
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