• Epilepsy & behavior : E&B · Jul 2011

    Case Reports

    Gabapentin-induced sexual dysfunction.

    • Kenneth R Kaufman and Peter J Struck.
    • Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, USA. kaufmakr@umdnj.edu
    • Epilepsy Behav. 2011 Jul 1; 21 (3): 324-6.

    AbstractSexual dysfunction is a key adverse effect leading to medication noncompliance. Psychotropic drugs associated with sexual dysfunction include antiepileptic drugs, antidepressants, and antipsychotics. Gabapentin, frequently used off-label to treat psychiatric and pain disorders, has previously been reported to cause sexual dysfunction at a minimum total daily dose of 900 mg. This report addresses dose-dependent gabapentin-induced sexual dysfunction reaching total sexual dysfunction (loss of libido, anejaculation, anorgasmia, and impotence) at a total daily dose of only 300 mg.Copyright © 2011 Elsevier Inc. All rights reserved.

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