• Anaesth Intensive Care · Sep 2009

    Case Reports

    Continuous venovenous haemodiafiltration for metformin-induced lactic acidosis.

    • L T T Pan and G MacLaren.
    • Department of Anaesthesia, National University Hospital, Singapore.
    • Anaesth Intensive Care. 2009 Sep 1; 37 (5): 830-2.

    AbstractA 74-year-old man with cardiac failure and renal impairment was admitted to the cardiothoracic intensive care unit with metformin-induced lactic acidosis and shock. He was successfully treated with high-dose (80 ml/kg/hour) continuous venovenous haemodiafiltration. Lactic acidosis is a known complication of metformin and is associated with a high mortality. The use of high-dose continuous venovenous haemodiafiltration for this condition has not previously been reported.

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