• Injury · Jun 2016

    Review

    Bone mechanical properties and changes with osteoporosis.

    • Georg Osterhoff, Elise F Morgan, Sandra J Shefelbine, Lamya Karim, Laoise M McNamara, and Peter Augat.
    • Division of Orthopaedic Trauma, Department of Orthopaedic Surgery, University of British Columbia, Vancouver, British Columbia, Canada.
    • Injury. 2016 Jun 1; 47 Suppl 2: S11-20.

    AbstractThis review will define the role of collagen and within-bone heterogeneity and elaborate the importance of trabecular and cortical architecture with regard to their effect on the mechanical strength of bone. For each of these factors, the changes seen with osteoporosis and ageing will be described and how they can compromise strength and eventually lead to bone fragility. © 2016 Elsevier Ltd. All rights reserved.

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