• Pain · Jun 1981

    Opiate pharmacology and individual differences. II. Somatosensory evoked potentials.

    • M S Buchsbaum, G C Davis, R Coppola, and D Naber.
    • Pain. 1981 Jun 1; 10 (3): 367-77.

    AbstractSomatosensory evoked potentials (EPs) to stimuli ranging from barely perceptible to painful were recorded in 153 normal adults. Reliability of amplitude and amplitude/intensity slopes were demonstrated in 29 individuals tested twice, two or more weeks apart. In randomized, double-blind placebo controlled trials, both aspirin and morphine significantly diminished N120 component at high stimulus intensities. Age, sex and pharmacological effects paralleled those found with psychophysical techniques in part I of this study.

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