-
Jornal de pediatria · Jul 2008
Case ReportsSedation of hypercyanotic spells in a neonate with tetralogy of Fallot using dexmedetomidine.
- Hideaki Senzaki, Hirotaka Ishido, Yoichi Iwamoto, Mio Taketazu, Toshiki Kobayashi, Toshiyuki Katogi, and Shunei Kyo.
- Department of Pediatric Cardiology and Pediatrics, Saitama Heart Institute, Saitama Medical University Hospital, Saitama, Japan. hsenzaki@saitama-med.ac.jp
- J Pediatr (Rio J). 2008 Jul 1; 84 (4): 377-80.
ObjectiveSedation is an important step in the management of patients with hypercyanotic spells associated with tetralogy of Fallot (TOF) to ameliorate and prevent recurrence of cyanosis. This case report illustrates the effectiveness of dexmedetomidine-induced sedation in the management of hypercyanotic spells in a neonate with TOF.DescriptionAn 8-day-old term newborn patient with TOF showed hypercyanotic spells, as indicated by an abrupt decrease in arterial saturation (SpO2) level measured by a pulse oximeter from 80% to as low as 50%, when the patient became irritable and agitated. We started continuous infusion of dexmedetomidine at a dose of 0.2 microg/kg/min without a loading bolus injection. About half an hour after commencement of dexmedetomidine infusion, the patient reached an acceptable level of sedation, together with a drop in heart rate by approximately 20 beats/min. There was no apparent respiratory depression or marked change in blood pressure. SpO2 was also stable during dexmedetomidine infusion. The patient underwent a successful Blalock-Taussig shunt operation on the next day of admission.CommentsDexmedetomidine may be useful for the management of hypercyanotic spells in pediatric patients with TOF.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*
,_underline_
or**bold**
. - Superscript can be denoted by
<sup>text</sup>
and subscript<sub>text</sub>
. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3.
, hyphens-
or asterisks*
. - Links can be included with:
[my link to pubmed](http://pubmed.com)
- Images can be included with:
![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
- For footnotes use
[^1](This is a footnote.)
inline. - Or use an inline reference
[^1]
to refer to a longer footnote elseweher in the document[^1]: This is a long footnote.
.