• Clin. Infect. Dis. · Jan 2015

    Protracted fecal shedding of HEV during ribavirin therapy predicts treatment relapse.

    • Florence Abravanel, Sébastien Lhomme, Lionel Rostaing, Nassim Kamar, and Jacques Izopet.
    • INSERM, U1043, Centre de Physiopathologie de Toulouse Purpan CHU Toulouse, Hôpital Purpan, Laboratoire de virologie, Centre National de Référence Hépatite E, Institut fédératif de biologie de Purpan.
    • Clin. Infect. Dis. 2015 Jan 1; 60 (1): 96-9.

    AbstractTwenty-four solid-organ-transplant recipients with chronic hepatitis E virus (HEV) infections were given ribavirin therapy for 3 months. All the patients with protracted fecal HEV shedding during treatment suffered a relapse. Monitoring HEV fecal excretion could be used to determine the optimal duration of ribavirin therapy.© The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

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