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Best Pract Res Clin Anaesthesiol · Dec 2002
ReviewEffect of post-operative analgesia on patient morbidity.
- Christopher L Wu and Matthew D Caldwell.
- Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA.
- Best Pract Res Clin Anaesthesiol. 2002 Dec 1; 16 (4): 549-63.
AbstractThe pathophysiology that commonly follows surgery results in detrimental physiological effects and may be associated with post-operative mortality and morbidity. The use of post-operative epidural analgesia, but not systemic opioids, may attenuate some of these adverse physiological effects and result in a decrease in patient-related morbidity post-operatively. Randomized trials suggest that the perioperative use of epidural analgesia may facilitate return of gastrointestinal function, attenuate hypercoagulable events and diminish post-operative pulmonary complications. A multimodal approach incorporating the use of epidural analgesia to control perioperative pathophysiology will facilitate the patient's recovery.
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