• Modern rheumatology · Feb 2010

    Case Reports

    Acute respiratory distress syndrome associated with rapid aggravation of rheumatoid arthritis.

    • Shunsuke Mori, Isamu Cho, and Mineharu Sugimoto.
    • Department of Rheumatology, Clinical Research Center for Rheumatic Disease, NHO Kumamoto Saishunsou National Hospital, 2659 Suya, Kohshi, Kumamoto, 861-1196, Japan. moris@saisyunsou1.hosp.go.jp
    • Mod Rheumatol. 2010 Feb 1; 20 (1): 77-80.

    AbstractA 76-year-old woman with seropositive rheumatoid arthritis (RA) developed acute respiratory distress syndrome (ARDS) following an appearance of severe inflammatory symptoms in multiple synovial joints. High-dose pulse therapy with methylprednisolone induced a marked improvement in pulmonary conditions. To the best of our knowledge, this is the first case in the literature to show a causal relationship between ARDS and RA. We should be alert to the possibility that ARDS can occur as an acute-type pulmonary complication of RA, particularly when patients show rapid aggravation of rheumatic activity.

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