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- V Hjorth and G Stenlund.
- Department of Anaesthesiology, Mälarsjukhuset, Eskilstuna, Sweden.
- Scand. J. Infect. Dis. 2000 Jan 1; 32 (5): 511-4.
AbstractPlasmapheresis is one of the methods which has been tried in the effort to influence the course of severe sepsis with septic shock and to improve survival rates. This is a retrospective study of 17 consecutive patients with septic shock who were treated with acute plasmapheresis. Nine out of 16 patients with verified etiology suffered from infections with Gram-positive bacteria. Three (18%) of the treated patients died. The estimated mortality rate based on the patients' initial APACHE II scores was 62%. No serious side-effects of treatment were observed. This study indicates that plasmapheresis is a safe treatment for patients with septic shock and has a positive effect on survival. Prospective, randomized studies would be valuable to determine the role of plasmapheresis in the management of patients with septic shock.
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