• Si-cheng Xu, Yi-fen Huang, Xi-yan Wang, and Min Jia.
• Respiratory Department, First Affiliated Hospital of Xinjiang Medical University, Urmqi 830000, Xinjiang, China.
• Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2003 Jun 1; 15 (6): 354-7.

ObjectiveTo investigate the factors affecting the effect of noninvasive positive pressure ventilation (NIPPV) on treatment of acute respiratory distress syndrome (ARDS).MethodsAccording to the disease-induced factors, patients with ARDS were divided into two groups: group A (pulmonary factors), group B (extra-pulmonary factors). Different kinds of ventilator s were used in the course of NIPPV via facial or nasal mask. The mode, biphasic intermittent positive airway pressure (BiPAP, BiPAP vision), pressure support ventilation (PSV) + positive end-expiratory pressure (PEEP) or synchronized intermittent mandatory ventilation (SIMV) + PSV + PEEP, was administered. After 3-10 hours, the patients who were not fit to NIPPV were conducted intubation.ResultsGroup A had 9 cases, of whom 5 cases were treated with NIPPV all the time, while in group B, 14 cases, of whom 12 cases The cure rate of group A by NIPPV was 55.6% (5/9), while that of group B was 85.7% (12/14), P<0.05.ConclusionSelecting proper indication, reasonable ventilator mode and parameters, and improving the unfavorable factors can contribute to the decrease of intubation rate.

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