• Br J Anaesth · Sep 2002

    Case Reports

    Coronary artery spasm and non-Q-wave myocardial infarction following intravenous ephedrine in two healthy women under spinal anaesthesia.

    • A Wahl, F R Eberli, D A Thomson, and M Luginbühl.
    • Swiss Cardiovascular Centre, University Hospital of Bern, CH-3010 Bern, Switzerland.
    • Br J Anaesth. 2002 Sep 1; 89 (3): 519-23.

    AbstractVasovagal episodes occur frequently in young healthy patients undergoing venous cannulation and loco-regional anaesthesia. We report two cases of severe coronary vasospasm and non-Q-wave infarction in healthy young women after administration of ephedrine for vasovagal symptoms at the onset of spinal anaesthesia. In the light of unopposed vagal predominance pre-disposing patients to coronary vasospasm, even in young healthy patients, atrophine and not ephedrine should be the first line treatment for bradycardia with or without hypotension under spinal anaesthesia.

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