• Cir Cir · May 2003

    Review

    [Innate immunity, Toll receptor and sepsis].

    • Raúl Carrillo-Esper.
    • Postgrado de Medicina del Enfermo en Estado Crítico, Servicio de Terapia Intensiva HCSAE PEMEX. seconsapcma@mail.medinet.net.mx
    • Cir Cir. 2003 May 1; 71 (3): 252-8.

    AbstractThe innate immune response is the first line of defense against infection. Toll-like receptors (TLRs) recognize bacterial lipopolysaccharide and other pathogen-associated molecular patterns (PAMPs). Intracellular signals initiated by interaction between Toll receptors and specific PAMPs results in inflammatory response. Sepsis and septic shock are the result of an exaggerated inflammatory systemic response induced by innate immune dysregulation.

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