• Robert W Gereau, Kathleen A Sluka, William Maixner, Seddon R Savage, Theodore J Price, Beth B Murinson, Mark D Sullivan, and Roger B Fillingim.
• The American Pain Society, Glenview, Illinois; Washington University Pain Center and Department of Anesthesiology, Washington University School of Medicine, St. Louis, Missouri.
• J Pain. 2014 Dec 1; 15 (12): 1203-14.

UnlabelledChronic pain represents an immense clinical problem. With tens of millions of people in the United States alone suffering from the burden of debilitating chronic pain, there is a moral obligation to reduce this burden by improving the understanding of pain and treatment mechanisms, developing new therapies, optimizing and testing existing therapies, and improving access to evidence-based pain care. Here, we present a goal-oriented research agenda describing the American Pain Society's vision for pain research aimed at tackling the most pressing issues in the field.PerspectiveThis article presents the American Pain Society's view of some of the most important research questions that need to be addressed to advance pain science and to improve care of patients with chronic pain.Copyright © 2014 American Pain Society. Published by Elsevier Inc. All rights reserved.

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