• Xiujun Cai, Diyu Huang, Yiping Mu, and Shuyou Peng.
• Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China. cxjzu@hotmail.com
• Chin. J. Traumatol. 2002 Jun 1; 5 (3): 180-5.

ObjectiveTo find out the optimal concentration, infusion rate and dosage of saline for resuscitation.MethodsForty-five dogs were used to establish hypovolemic shock models. The dogs were resuscitated with saline of different concentrations and different dosages under different infusion rates, and the resuscitation results were compared.ResultsThe best concentration was 7.5%, the best rate of infusion 20 ml/min (a volume equivalent to 15% of the shed blood) and the best dosage 5.71 ml/kg. The method was effective for resuscitation, the mean arterial pressure (MAP) could be elevated to 89% of the baseline, and this MAP could be kept for more than one hour.ConclusionsUsing 7.5% sodium chloride solution equivalent to 15% of the shed blood at an infusion rate of 20 ml/min can achieve a best resuscitation result.

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