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Ned Tijdschr Geneeskd · Mar 2003
Comment Case Reports[Missing spleen: indication for pneumococcal vaccination].
- G W van Dijk, H J van Leeuwen, J van Gijn, and I M Hoepelman.
- Afd. Neurologie, Universitair Medisch Centrum Utrecht, Postbus 85.500, 3508 GA Utrecht.
- Ned Tijdschr Geneeskd. 2003 Mar 8; 147 (10): 425-8.
AbstractTwo female patients, aged 39 and 52 years, developed severe pneumococcal meningitis. Both patients had undergone splenectomy in the past (one after trauma and one for idiopathic thrombocytopenic purpura) and pneumococcal vaccination was only given immediately after the splenectomy. After antibiotic treatment and intensive care one patient remained disabled and the other patient died. There is a higher risk of developing severe sepsis after splenectomy, with Streptococcus pneumoniae being the causative micro-organism in more than 50% of cases. Vaccination after splenectomy in order to prevent a severe sepsis syndrome is very important. Indications for the 7 valent pneumococcal conjugate vaccine and the 23 valent polysaccharide vaccine are given.
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