• Pediatr. Clin. North Am. · Dec 1988

    Review

    Children as participants in medical research.

    • M A Grodin and J J Alpert.
    • Boston University School of Medicine, Massachusetts.
    • Pediatr. Clin. North Am. 1988 Dec 1; 35 (6): 1389-401.

    AbstractThe use of children in research raises the questions about proper justification, assessment of benefit in relation to risk, ability to consent, compensation, and the just selection of subjects. Although substantive and procedural standards have evolved, subpopulations of vulnerable children created new challenges and concerns.

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