• Run-han Li, Yong Zeng, Yue-jian Wang, Yuan-xin Zhao, Wei-xiong Chen, and Fang Yang.
• Departments of Otorhinolaryngology, First People's Hospital of Foshan, Foshan 528000, China. lrhan@fsyyy.com
• Nan Fang Yi Ke Da Xue Xue Bao. 2006 May 1; 26 (5): 661-3.

ObjectiveTo investigate the perioperative management of severe obstructive sleep apnea hypopnea syndrome (OSAHS).MethodsFifty-three patients with severe OSAHS received uvulopalatopharyngoplasty with uvula preservation and radiofrequency tongue base reduction. All the patients were treated with automated continuous positive airway pressure (CPAP) for 3-7 days before operation and automated antibiotic therapy administered in the oropharynx, with 24 h ECG monitoring postoperatively. Polysomnography were carried out before and 6 months after surgery.ResultsThe preoperative apnea hypopnea index (AHI) and lowest SaO(2) (LSaO(2)) were 58.4-/+5.1/h and 0.650-/+0.059, respectively, which were 15.5-/+3.2/h and 0.864-/+0.064 at 6 months after surgery, respectively, showing significant changes after surgery (P<0.01). Dyspnea occurred in 2 cases after operation, intraoperative bleeding in 1 case, primary bleeding in 2 cases and hypertension crisis in 1 case.ConclusionSevere OSAHS patients are subject to great surgical risk. Application of auto-CPAP before operation can significantly improve the patients' tolerance of surgery and anesthesia, and reduce the surgical risks and preoperative complications.

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