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Letter Case Reports
A 61-year-old woman with osteomalacia and a thoracic spine lesion.
- Ann E Marshall, Sarah E Martin, Narasimhan P Agaram, Jey-Hsin Chen, Eric M Horn, Annette C Douglas-Akinwande, and Eyas M Hattab.
- Brain Pathol. 2010 Mar 1; 20 (2): 499-502.
AbstractPhosphaturic mesenchymal tumor, mixed connective tissue variant (PMT-MCT) is a rare, largely benign, mesenchymal neoplasm almost invariably associated with oncogenic osteomalacia. It is generally found in the soft tissue and bone of the extremities. We report a case of a 61-year-old female with long-standing osteomalacia who was found to have PMT-MCT of the thoracic spine. There have been very few previously reported cases of PMT involving the spinal vertebrae and neuropathologists should be aware of this lesion. Recognition of PMT-MCT is critical for optimal patient care since complete surgical resection without additional therapy is curative.
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