• Dent. Clin. North Am. · Oct 2010

    Review

    Allergic reactions to local anesthetic formulations.

    • Steven J Speca, Sean G Boynes, and Michael A Cuddy.
    • Department of Anesthesiology, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA 15261, USA. drspeca@yahoo.com
    • Dent. Clin. North Am. 2010 Oct 1; 54 (4): 655-64.

    AbstractTrue allergic reactions to local anesthetics are rare adverse reactions. At the most, they represent less than 1% of all adverse local anesthetic reactions. When true allergic reactions have been confirmed, the reactions are most commonly the type I anaphylactic and type IV delayed hypersensitivity responses. The type I immediate hypersensitivity reactions are the most severe and may be life-threatening. In the event a potential allergic reaction occurs in a dental office, the dentist needs to properly evaluate the events leading up to the reaction and provide a differential diagnosis. A referral should be given to any patient when an allergic reaction cannot be ruled out as an intravascular injection, toxic overdose, psychogenic reaction, or an idiosyncratic event.Copyright © 2010 Elsevier Inc. All rights reserved.

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