• Eur. J. Obstet. Gynecol. Reprod. Biol. · Jul 1990

    Epidural analgesia and its effect on umbilical artery flow velocity waveform patterns in uncomplicated labour and labour complicated by pregnancy-induced hypertension.

    • G J Mires, J Dempster, N B Patel, and D J Taylor.
    • Department of Obstetrics and Gynaecology, Ninewells Hospital and Medical School, Dundee, Scotland.
    • Eur. J. Obstet. Gynecol. Reprod. Biol. 1990 Jul 1; 36 (1-2): 35-41.

    AbstractUmbilical artery flow velocity waveforms were obtained using continuous-wave Doppler ultrasound to examine the effect of epidural analgesia on peak systolic/least diastolic ratio (A/B ratio) in 38 women in uncomplicated labour, and 12 women with pregnancy-induced hypertension (PIH). In the uncomplicated group there was no significant change in A/B ratio after epidural analgesia, but in the PIH group there was significant correlation between the fall in mean blood pressure and the fall in A/B ratio at 30 min after induction of epidural analgesia (r = 0.85, p less than 0.001). This suggests that epidural analgesia in PIH is associated with a reduction in placental resistance and may be beneficial to the fetus.

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