• J. Cutan. Pathol. · Jul 2014

    Case Reports

    Ponatinib-induced neutrophilic panniculitis.

    • May Zhang, Khaled M Hassan, Amy Musiek, and Ilana S Rosman.
    • School of Medicine, Washington University in St. Louis, Saint Louis, MO, USA.
    • J. Cutan. Pathol. 2014 Jul 1; 41 (7): 597-601.

    AbstractPonatinib is a bcr-abl tyrosine-kinase inhibitor (TKI) used to treat resistant and refractory chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia that express bcr-abl. Neutrophilic panniculitis has been described in rare cases of patients on other TKIs in the same class as ponatinib. We present the first case of neutrophilic panniculitis following treatment with ponatinib and summarize the other cases of panniculitis caused by TKIs.© 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

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