• Akemi Yamagishi, Kazuki Sato, Mitsunori Miyashita, Yasuo Shima, Yoshiyuki Kizawa, Megumi Umeda, Hiroya Kinoshita, Yutaka Shirahige, Miki Akiyama, Takuhiro Yamaguchi, and Tatsuya Morita.
• Department of Community Health Care, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan. Electronic address: tmorita@sis.seirei.or.jp.
• J Pain Symptom Manage. 2014 Oct 1;48(4):602-10.

ContextA recent mixed-methods study to evaluate the effects of a comprehensive regional palliative care program, the Japan Outreach Palliative Care Trial of the Integrated Model study, achieved broad positive outcomes at a regional level. This is a secondary analysis of patient outcomes.ObjectivesThe primary aims were to explore: 1) the changes in domains of patient-reported quality of care and quality of life after interventions, and 2) the changes in quality of care and quality of life of patients with different characteristics (i.e., performance status, age, and anticancer treatment).MethodsA region-representative sample of metastatic/locally advanced cancer patients in outpatient settings participated in questionnaire surveys before and after regional intervention. Responses were obtained from 859 of 1880 and 857 of 2123 in the pre- and postintervention surveys, respectively.ResultsAll subdomain scores of the quality of care, except for help with decision making, significantly improved in the postintervention survey. The percentages of the patients who reported that improvement was necessary decreased from 13% to 5.0%. Although there were no or only a marginally significant difference in total and subdomain scores of quality of life between preintervention and postintervention surveys, the subgroups of patients with a poor performance status and those receiving no anticancer treatment achieved a significant improvement in the quality of life.ConclusionAlthough average changes in patient-reported outcomes were relatively small in the total sample of patients, the intervention seemed to provide tangible benefits for the patients with poor general conditions. A future regional intervention trial should include patient outcomes in those with a poor general condition to evaluate the net effects of the program.Copyright © 2014 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

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