• Pathologie-biologie · Dec 2012

    Review

    Pathogenic free-living amoebae: epidemiology and clinical review.

    • H Trabelsi, F Dendana, A Sellami, H Sellami, F Cheikhrouhou, S Neji, F Makni, and A Ayadi.
    • Fungal and parasitic molecular biology laboratory, School of Medicine Sfax, University of Sfax, Magida Boulila Street, 3029 Sfax, Tunisia.
    • Pathol. Biol. 2012 Dec 1; 60 (6): 399-405.

    AbstractFree-living amoebae are widely distributed in soil and water. Small number of them was implicated in human disease: Acanthamoeba spp., Naegleria fowleri, Balamuthia mandrillaris and Sappinia diploidea. Some of the infections were opportunistic, occurring mainly in immunocompromised hosts (Acanthamoeba and Balamuthia encephalitis) while others are non opportunistic (Acanthamoeba keratitis, Naegleria meningoencephalitis and some cases of Balamuthia encephalitis). Although, the number of infections caused by these amoebae is low, their diagnosis was still difficult to confirm and so there was a higher mortality, particularly, associated with encephalitis. In this review, we present some information about epidemiology, ecology and the types of diseases caused by these pathogens amoebae.Copyright © 2012 Elsevier Masson SAS. All rights reserved.

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