• Cadernos de saúde pública · Feb 2006

    Randomized Controlled Trial Comparative Study

    [Randomized clinical trial: effectiveness of the cognitive-behavioral approach and the use of nicotine replacement transdermal patches for smoking cessation among adults in Rio de Janeiro, Brazil].

    • Ubirani Barros Otero, Cristina de Abreu Perez, Moysés Szklo, Gilcenira Ataliba Esteves, Mariana Marques dePinho, André Salem Szklo, and Silvana Rubano B Turci.
    • Coordenação de Prevenção e Vigilância, Instituto Nacional de Câncer, Rua dos Inválidos 212, 2o andar, Rio de Janeiro, RJ 20231-020, Brazil. uotero@inca.gov.br
    • Cad Saude Publica. 2006 Feb 1; 22 (2): 439-49.

    AbstractRandomized clinical trial carried out to investigate the effectiveness of the cognitive-behavioral approach and nicotine replacement therapy with nicotine patches for smoking cessation. Participated 1,199 adults, volunteers, in Rio de Janeiro, Brazil, randomly assigned to 10 different groups: intensive brief counseling group (GB), with 1 or 2 sessions (G1-G2), and with 3 or 4 sessions (G3-G4), with/without nicotine replacement therapy (NRT). Abstinence proportions were estimated during 12 months. These proportions among participants not assigned to NRT were 20% (GB), 17% (G1-G2), and 23% (G3-G4); and among assigned NRT groups were 30% (GBA), 34% (G1A-G2A), and 33% (G3A-G4A). After multiple adjustments, the abstinence proportions ratios seemed to follow a "dose-response" pattern: compared to GB, the ratios were 0.85 (G1-G2), 1.13 (G3-G4), 1.51 (GBA), 1.66 (G1A-G2A), and 1.75 (G3A-G4A). The results suggest that use of NRT increases the abstinence proportion for cessation. The "dose-response" pattern suggests that cognitive-behavioral could be the reasonable option in the smoking cessation therapy.

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