• James P Isbister.
• Department of Haematology, Royal North Shore Hospital of Sydney, University of Sydney, St. Leonards, Australia. jisbiste@med.usyd.edu.au
• Transfus Apher Sci. 2002 Aug 1; 27 (1): 19-28.

AbstractClinical decision making in transfusion medicine has received greater attention in recent years driven by concern about the potential hazards, especially since the recognition that HIV can be transmitted by homologous blood transfusion. These concerns about the risks of homologous transfusion has precipitated interest in the appropriateness of many transfusions and in the decision making processes in transfusion medicine. There has been increasing expenditure on the blood supply side to address the real or perceived potential infectious hazards. This has at times been to the detriment of the patient demand side of the homologous donor blood chain. This imbalance is now being addressed with the development of evidence based clinical guidelines for individual blood components, transfusion monitoring systems and quality assurance programmes. In this review of the process of clinical decision making in transfusion medicine and the factors involved in the ensuring a patient receives a safe and effect transfusion are addressed. The responsibilities of the patient's clinical carers are emphasised.

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