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Randomized Controlled Trial Comparative Study Clinical Trial
Metoclopramide and prochlorperazine do not decrease propofol hypnotic requirements.
- P B Ali and S G Graham.
- University Department of Anaesthesia, Royal Victoria Infirmary.
- Anaesthesia. 1995 Nov 1; 50 (11): 990-1.
AbstractOne hundred patients scheduled for minor surgery were given either saline, metoclopramide 0.1 mg.kg-1 or 0.2 mg.kg-1, or prochlorperazine 0.1 mg.kg-1 or 0.2 mg.kg-1 before induction of anaesthesia with a fixed rate infusion of propofol. Neither metoclopramide nor prochlorperazine reduced the induction dose of propofol. The possibility that these agents increased the induction dose could not be excluded.
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