• Dennis C Turk, Elizabeth J Dansie, Hilary D Wilson, Bruce Moskovitz, and Myoung Kim.
• Department of Anesthesiology & Pain Medicine and Center for Pain Research on Impact, Measurement, & Effectiveness, University of Washington, Seattle, Washington, USA.
• Pain Med. 2014 Apr 1;15(4):625-36.

BackgroundTamper-resistant opioid formulations (TRFs) have recently been the target of active development in an effort to deter opioid misuse and abuse.ObjectiveTo understand factors that are predictive of physicians' likelihoods of prescribing TRFs to patients with chronic noncancer pain (CNCP).DesignA cross-sectional survey was conducted, utilizing a questionnaire of clinicians' attitudes and opinions about opioids for CNCP (Clinicians' Attitudes about Opioids Scale) to explore beliefs about and likelihood of prescribing TRFs.SubjectsA nationally representative sample of 1,535 practicing physicians throughout the United States.MethodsA stepwise hierarchical multiple linear regression analysis was conducted to estimate if physician characteristics, opinions, or geographic region categorized according to state rates of mortality by drug overdose and milligrams of opioids prescribed by state were predictive of the likelihood of prescribing TRFs.ResultsBoard certification in Pain Medicine and prescribing opioids to a higher volume of CNCP patients were significantly predictive of a reported likelihood of prescribing TRFs, in addition to concerns about possible misuse and abuse of opioids, beliefs in the effectiveness of opioids for CNCP, and greater satisfaction with education and training in pain management this set of factors accounted for 21% of the model variance. Rates of mortality by drug overdose and opioid prescription volume by location were not predictive of TRF usage.ConclusionsReducing physician concerns about potential misuse and abuse of opioids through additional education in pain management and dissemination of information about the potential benefits and availability of TRFs should influence physicians' attitudes about and the adoption of TRFs.Wiley Periodicals, Inc.

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