[Acid-base equilibrium of the arterial blood of subjects with

Minerva medica · Sep 1976

Case Reports

[Acid-base equilibrium of the arterial blood of subjects with grave hypercapnia subjected to mechanical ventilation with the iron lung (concerning 2 cases of post-hypercapnic alkalosis)].

Two cases of severe chronic respiratory insufficiency in severely acute phase with disturbances in acid base balance characterized by serious gaseous acidosis are reported. Therapy was based essentially on controlled ventilotherapy using an iron lung and considerable improvements were achieved clinically with practically total normalization of the acid base imbalance after only a few hours of treatment. In the following days, however, a picture of metabolic alkalosis established itself and this is discussed and interpreted as an expression of post-hypercapnic hypochloraemia.

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- A Ferrara, R Numeroso, and G Fumagalli.
- Minerva Med. 1976 Sep 22; 67 (44): 2877-82.
AbstractTwo cases of severe chronic respiratory insufficiency in severely acute phase with disturbances in acid base balance characterized by serious gaseous acidosis are reported. Therapy was based essentially on controlled ventilotherapy using an iron lung and considerable improvements were achieved clinically with practically total normalization of the acid base imbalance after only a few hours of treatment. In the following days, however, a picture of metabolic alkalosis established itself and this is discussed and interpreted as an expression of post-hypercapnic hypochloraemia.

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[Acid-base equilibrium of the arterial blood of subjects with grave hypercapnia subjected to mechanical ventilation with the iron lung (concerning 2 cases of post-hypercapnic alkalosis)].

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