• José Barros, Alexandre Mendes, Ilda Matos, and José Pereira-Monteiro.
• Serviço de Neurologia, Hospital de Santo António (HSA), Centro Hospitalar do Porto (CHP), Largo Professor Abel Salazar, 4099-001 Porto, Portugal, josebarros.neuro@hgsa.min-saude.pt
• J Headache Pain. 2012 Oct 1;13(7):581-5.

IntroductionNeuropsychological symptoms are rare in familial hemiplegic migraine (FHM). There are no reports of psychotic symptoms in FHM type 2 (ATP1A2). We examined a family with a FHM phenotype due to a M731T mutation in ATP1A2. A 10-year follow-up allowed us to observe complex auras, including psychotic symptoms in two siblings.Case ReportMale, 48 years old, with an aura that included complex illusions with a feeling of time travelling, coincident with other aura features. The aura was regarded as mystical by the patient. Female, 38 years old, with a complex migraine aura, during which she believed she had the ability to time travel and was being followed by lobbyists who wanted to steal this ability from her.DiscussionFHM type 2 must be included in the list of differential diagnoses of acute psychosis in patients with a previous history of migraine aura.

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