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- B Bannwarth and M Kostine.
- Department of Rheumatology, Pellegrin Hospital Center, University Hospital of Bordeaux, Bordeaux, France; Department of Therapeutics, Division of Health, University of Bordeaux, Bordeaux, France.
- Clin. Pharmacol. Ther. 2015 Feb 1; 97 (2): 122-4.
AbstractExisting analgesics fail to provide adequate pain relief in a significant proportion of patients complaining of chronic pain. Furthermore, their use is limited by tolerability and safety concerns. Thus, there is a huge unmet need for effective and safe innovative painkillers. Considering the major role of nerve growth factor (NGF) in the generation and maintenance of a wide range of pain states, the issue is whether anti-NGF biologics under development might offer such an opportunity.© 2014 American Society for Clinical Pharmacology and Therapeutics.
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