• B R Toorenvliet, R Th J Kortekaas, and A H P Niggebrugge.
• Ziekenhuis Bronovo, afd. Heelkunde, Postbus 96.900, 2509 JH Den Haag.
• Ned Tijdschr Geneeskd. 2002 Sep 7; 146 (36): 1696-8.

AbstractA 30-year-old man with flu-like symptoms for several weeks presented at the emergency room with pain in the left upper abdomen. There was no history of trauma. The patient had a spontaneous rupture of the spleen due to mononucleosis infectiosa. He was successfully treated with conservative management during a 7-day period of hospitalisation. Spontaneous splenic rupture is a rare but potentially lethal complication of infectious mononucleosis. Alarming symptoms are left upper abdominal pain, worsening during inspiration, and haemodynamic instability. Although splenectomy is the accepted treatment for haemodynamically unstable patients, some patients, may be adequately treated with conservative management. They should be observed during the critical phase and must comply to a period of restricted physical activity after they are discharged from the hospital. There is no consensus about the length or content of this restriction period.

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