• Pain Res Manag · Jan 2005

    Review

    Guidelines for the use of cannabinoid compounds in chronic pain.

    • A J Clark, M E Lynch, M Ware, P Beaulieu, I J McGilveray, and D Gourlay.
    • University of Calgary, Calgary, Alberta. john.clark@calgaryhealthregion.ca
    • Pain Res Manag. 2005 Jan 1;10 Suppl A:44A-6A.

    ObjectiveTo provide clinicians with guidelines for the use of cannabinoid compounds in the treatment of chronic pain.MethodsPublications indexed from 1990 to 2005 in the National Library of Medicine Index Medicus were searched through PubMed. A consensus concerning these guidelines was achieved by the authors through review and discussion.ResultsThere are few clinical trials, case reports or case series concerning the use of cannabinoid compounds in the treatment of chronic pain. There are no randomized clinical trials examining the use of herbal cannabis in the treatment of chronic pain.ConclusionsA practical approach to the treatment of chronic pain with cannabinoid compounds is presented. Specific suggestions about the off-label dosing of nabilone (Cesamet, Valeant Canada limitee/Limited) and dronabinol (Marinol, Solvay Pharma Inc, Canada) in the treatment of chronic pain are provided.

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