• Am. J. Surg. · Apr 2008

    Comparative Study

    Effect of systemic corticosteroids on elective left-sided colorectal resection with colorectal anastomosis.

    • Christophe Trésallet, Benoit Royer, Gaëlle Godiris-Petit, and Fabrice Menegaux.
    • Department of General and Digestive Surgery, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Université Pierre et Marie Curie (Paris VI), 75651 Paris Cedex 13, France. christophe.tresallet@psl.aphp.fr
    • Am. J. Surg. 2008 Apr 1; 195 (4): 447-51.

    BackgroundThe impact of systemic steroid therapy on surgical outcome after elective left-sided colorectal resection with rectal anastomosis is not well known.MethodsWe compared 606 consecutive patients including 53 patients who were on steroids and undergoing surgery between 1995 and 2005.ResultsPostoperative mortality and anastomotic leakage rates were equivalent. The postoperative complications rate, especially infections, was higher in steroid-treated patients than in non-steroid-treated patients: 38% (20 of 53 patients) versus 25% (139 of 553 patients), respectively (P = .046). In the steroid group, univariate analysis revealed 3 significant risk factors for postoperative complications: blood transfusion, preoperative anticoagulation, and chronic respiratory failure. In a multivariate analysis, blood transfusion and chronic respiratory failure remained independent factors for postoperative complications.ConclusionPatients on steroids have a higher incidence of postoperative complications after elective left-sided colorectal resection with rectal anastomosis.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…